Macomb is an unincorporated community in Wright County, Missouri, United States. It is located on Route K about 2 miles south of U.S. Route 60. The post office and a couple of businesses are located at the interchange on the outer road and MoDOT has posted signs for the town at this location.A post office called Macomb has been in operation since 1886. The community has the name of the local Macomb family.